Rapasin 8

Rapasin 88mg

Type:10 Capsules

Generic Name:Silodosin

Manufacturer:Unimed Unihealth Pharmaceuticals Ltd.

Price:250.00

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Indication

Treating the signs and symptoms of enlarged prostate (benign prostatic hyperplasia [BPH]).

Adult Dose

Benign Prostatic Hyperplasia Adults PO 8 mg once daily with a meal. Hepatic Impairment Mild-to-moderate impairment (Child-Pugh class A or B): Dose adjustment not necessary Severe Impairment: (Child-Pugh class C): Contraindicated (not studied)

Renal Dose

Renal Impairment CrCl <50 mL/min: Dose adjustment not necessary CrCl 30-50 mL/min: 4 mg PO qDay CrCl <30 mL/min: Contraindicated

Contraindication

Hypersensitivity.

Mode of Action

Selectively blocks postsynaptic alpha-1 adrenoreceptors located in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra.

Precaution

Impaired hepatic & renal function. Start treatment w/ a low dose (2 mg/dose).

Side Effect

>10% Retrograde ejaculation (28%) 1-10% Diarrhea (3%),Headache (2%),Insomnia ((1-2%),Dizziness (3%),Orthostatic hypotension (3%; increased in patients >65 years),Nasopharyngitis (2%),Nasal congestion (2%),Sinusitis (1-2%)

Interaction

Ketoconazole, digoxin.

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Drug International Ltd.

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Square Pharmaceuticals PLC.

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Popular Pharmaceuticals Ltd.

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