Picosul 10

Picosul 1010mg

Type:10 Tablets

Generic Name:Sodium picosulfate

Manufacturer:Opsonin Pharma Limited

Price:100.00

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Indication

Constipation, Bowel evacuation before investigational procedures

Administration

May be taken with or without food.

Adult Dose

Oral Constipation Adult: 5-10 mg as a single dose, usually at bedtime. Bowel evacuation before investigational procedures Adult: 10 mg, w/ Mg citrate, given in the morning and again in the afternoon of the day before examination.

Child Dose

Oral Constipation Child: 1 mth to <4 yr 0.25 mg/kg. Max: 5 mg; 4-10 yr 2.5-5 mg; >10 yr 5-10 mg. Doses are usually given at night. Bowel evacuation before investigational procedures Child: 1 mth to <4 yr 0.25 mg/kg. Max: 5 mg; 4-10 yr 2.5-5 mg; >10 yr 5-10 mg. Doses are usually given at night.

Contraindication

Acute inflammatory bowel diseases, severe dehydration, ileus or intestinal obstruction, severe painful and/or feverish acute abdominal conditions (e.g. appendicitis) potentially associated w/ nausea and vomiting.

Mode of Action

Sodium picosulfate is a locally acting laxative which has a dual action of stimulating the mucosa of both the large intestine causing colonic peristalsis and of the rectum causing increased motility and a feeling of rectal fullness.

Precaution

Childn. Pregnancy and lactation.

Side Effect

Abdominal discomfort (e.g. abdominal pain and cramps), diarrhoea. Rarely, allergic reactions (e.g. skin reactions, angioedema).

Interaction

Increased risk of electrolyte imbalance w/ diuretics or adreno-corticosteroids. Increased sensitivity to cardiac glycosides resulting from electrolyte imbalance. Reduced laxative action w/ antibiotics.

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