Type:Tablet
Generic Name:Pizotifen
Manufacturer:EDCL
Price:৳3.00
Headache, Migraine
May be taken with or without food.
Oral Prophylaxis of migraine; Prophylaxis of cluster headache Adult: Initially, 0.5 mg, increase gradually as necessary. Maintenance: 1.5 mg daily as a single dose at night or in 3 divided doses. Max: 4.5 mg daily (max ?3 mg/dose). Hepatic impairment: Dose adjustment may be needed.
Oral Prophylaxis of migraine; Prophylaxis of cluster headache Child: >2 yr Initially, 0.5 mg. May increase gradually up to 1.5 mg daily in divided doses (max 1 mg/dose).
Renal impairment: Dose adjustment may be needed.
Premature infants or neonates. Postural giddiness.
Pizotifen is a sedating antihistamine with strong serotonin antagonist and weak antimuscarinic properties. It also antagonises the action of tryptamine.
Patient w/ angle-closure glaucoma, urinary retention, epilepsy. Avoid abrupt withdrawal. Renal and hepatic impairment. Childn. Pregnancy and lactation. Patient Counselling This drug may cause drowsiness, somnolence and dizziness, if affected, do not drive or operate machinery. Monitoring Parameters Monitor hepatic function (prolonged use), wt gain, BP.
Increased appetite, nausea, wt gain, drowsiness, dizziness, dry mouth, fatigue, muscle pain or cramps, heavy or restless legs, fluid retention, facial flushing, reduced libido, exacerbation of epilepsy, dreaming, hepatic injury.
Enhances sedative effects of CNS depressants. Additive antimuscarinic action with other antimuscarinic drugs. May mask warning signs of damage caused by ototoxic drugs eg, aminoglycosides.
