Type:5ml drop
Generic Name:Gatifloxacin Eye prep
Manufacturer:The Ibn Sina Pharmaceutical Ind. Ltd.
Price:৳100.00
Bacterial conjunctivitis
Ophthalmic Bacterial conjunctivitis Adult: As 0.3% soln: Instill 1 drop 2 hrly into affected eye(s) while awake (up to 8 times daily) for the 1st 2 days then reduce to 1 drop 4 times daily while awake for the next 5 days.
Ophthalmic Bacterial conjunctivitis Child: >1 yr: As 0.3% soln: Instill 1 drop 2 hrly into affected eye(s) while awake (up to 8 times daily) for the 1st 2 days then reduce to 1 drop 4 times daily while awake for the next 5 days.
Patients with a history of hypersensitivity to Gatifloxacin, to other quinolones, or to any of the components in this medication. Eye drops should not be injected subconjunctivally, nor should it be introduced directly into the anterior chamber of the eye.
Gatifloxacin is a fluoroquinolone antibacterial which acts by inhibiting DNA synthesis in susceptible organisms via inhibition of both DNA gyrase (essential for bacterial reproduction) and topoisomerase IV (essential during bacterial cell division).
Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis. Avoid contaminating the applicator tip with material from the eye, fingers or other source.
1-10% Conjunctival irritation (5-10%),Incr. lacrimation (5-10%),Keratitis (5-10%),Papillary conjunctivitis (5-10%),Conjunctival hemorrhage (1-4%),Chemosis (1-4%),Dry eye (1-4%),Eye discharge (1-4%),Eye irritation (1-4%),Eye pain (1-4%),Eyelid swelling (1-4%),Red eye (1-4%),Visual acuity decr (1-4%),Taste disturbance (1-4%)
Additive effect w/ drugs that prolong QT interval e.g. antiarrhythmic agents (amiodarone, quinidine, sotalol), arsenic trioxide, cisapride, chlorpromazine, droperidol, mefloquine, dolasetron, mesoridazine, moxifloxacin, pimozide, tacrolimus, pentamidine, thioridazine, ziprasidone. Increased risk of blood glucose disturbances w/ drugs that alter blood glucose concentrations (e.g. antidiabetics). Systemic admin may elevate plasma concentrations of theophylline, interfere caffeine metabolism, enhance effects of oral anticoagulant (warfarin and its derivatives), and transient elevations in serum creatinine w/ ciclosporin.