Salpac IV

Salpac IV0.90%

Type:500ml

Generic Name:Sodium Chloride 0.9%

Manufacturer:Orion Pharma Ltd.

Price:67.44

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Indication

Dehydration, Excessive sweating, Water and electrolyte imbalance, Metabolic alkalosis, Diluting or dissolving drugs. Intra-ocular or topical irrigation during surgical procedure. Dry nasal membranes including dry or irritated nose resulting from cold and allergy medications. Removing thick fluid in the nose passages.

Adult Dose

Adult: IV Replacement of fluid and electrolytes As 0.9% soln: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Hypernatraemia As 0.9% soln: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Irrigation Irrigation of the bladder, eye, general skin and wound cleansing As 0.9% soln: Use as directed. Eye drop: 1 drop in the affected eye (s) every 3 or 4 hours or as directed by a physician. Nasal drop: Nasal congestion As 0.9% soln: Infants, children & adults : 2 drops in each nostril, 1-4 times a day

Child Dose

Child IV Replacement of fluid and electrolytes As 0.9% soln: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Hypernatraemia As 0.9% soln: Dosage depends on age, wt, clinical condition and laboratory determinations of the patient. Irrigation Irrigation of the bladder, eye, general skin and wound cleansing As 0.9% soln: Use as directed. Eye drop: 1 drop in the affected eye (s) every 3 or 4 hours or as directed by a physician. Nasal drop: Nasal congestion As 0.9% soln: Infants, children & adults : 2 drops in each nostril, 1-4 times a day

Contraindication

Conditions whereby admin of sodium chloride would be detrimental. Not to be used to induce emesis. Sustained release tablets: GI disorders associated with strictures or diverticula.

Mode of Action

Sodium chloride is the major extracellular cation. It is important in electrolyte and fluid balance, osmotic pressure control and water distribution as it restores sodium ions. It is used as a source of electrolytes and water for hydration, treatment of metabolic acidosis, priming solution in haemodialysis and treatment of hyperosmolar diabetes. It is also used as diluents for infusion of compatible drug additives. Nasal Preparation: It moisturizes the nose, helps to dissolve and loosen thick mucus.

Precaution

Hypertension, heart failure, peripheral or pulmonary oedema, impaired renal function, liver cirrhosis, preeclampsia. Maintain adequate water intake. Pregnancy. Inj of 3 or 5% sodium chloride solution should be given via a large vein at a rate not exceeding 100 ml/hr. Monitor fluid balance, serum electrolytes and acid base balance espcially during prolonged treatment. Caution when used in patients who are receiving corticosteroids or corticotropin. Nasal prep: If baby begin to cough after applying this drug, allow him to sit up or help him to sit.

Side Effect

Hypernatraemia; thirst, reduced salivation and lachrymation, fever, tachycardia, hypertension, headache, dizziness, restlessness, irritability and weakness. Burning or irritation of the eye may occur temporarily when first applied. Other side effects are redness, pain, swelling in or around the eyes, sensitivity to light, and headache. Potentially Fatal: Intra-amniotic inj of hypertonic solutions: Disseminated intravascular coagulation, renal necrosis, cervical and uterine lesions, pulmonary embolism, pneumonia and death.

Interaction

May affect serum concentrations of lithium.

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