Type:7 Capsules
Generic Name:Dutasteride
Manufacturer:Drug International Ltd.
Price:৳84.28
Benign prostatic hyperplasia (BPH)
May be taken with or without food.
Oral Benign prostatic hyperplasia Adult: 500 mcg once daily for at least 6 mth. Hepatic impairment: Severe: Contraindicated.
Renal impairment: Dose adjustment not necessary
Severe liver impairment; pregnant women, children, adolescent.
Dutasteride has antiandrogenic properties. It inhibits 5alpha-reductase, thus preventing the conversion of testosterone to 5?-dihydrotestosterone which is the main androgen involved in causing prostate enlargement.
Excreted in semen therefore use of condom is recommended. Women of childbearing potential should avoid handling dutasteride capsules. Advisable to exclude other causes of benign prostatic hypertrophy (e.g. prostate cancer, infection) before initiating therapy. Lactation: Excretion in milk unknown/contraindicated
1-10% Impotence,Decreased libido,Ejaculation disorder,Breast disorders/gynecomastia <1% Dizziness Frequency Not Defined Cardiac failure,Prostate cancer (high grade)
Pregnancy category: X Lactation: Excretion in milk unknown/contraindicated
Plasma concentrations may be increased when used concomitantly w/ moderate or potent CYP3A4 inhibitors.
