Medicase - Hebasol - 10gm tube - 0.05% - Halobetasol Propionate 0.05% Topical

Hebasol0.05%

Type:10gm tube

Generic Name:Halobetasol Propionate 0.05% Topical

Manufacturer:Pharmasia Ltd.

Price:৳90.00

Indication

Psoriasis, Eczema, Corticosteroid-responsive dermatoses

Administration

A thin layer should be applied to the affected skin once or twice daily and rub in gently and completely.

Adult Dose

Inflammatory, Pruritic & Steroid-Responsive Dermatoses Apply topically to affected area(s) BID Not to exceed 50 g/week; do not use longer than 2 consecutive weeks

Child Dose

Inflammatory, Pruritic & Steroid-Responsive Dermatoses <12 years: Safety and efficacy not established >12 years: Apply topically to affected area(s) BID Not to exceed 50 g/wk; do not use longer than 2 wk

Contraindication

Halobetasol Propionate Cream/Ointment is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.

Mode of Action

Corticosteroids decrease inflammation by stabilizing leukocyte lysosomal membranes, preventing release of destructive acid hydrolases from leukocytes; inhibiting macrophage accumulation in inflamed areas; reducing leukocyte adhesion to capillary endothelium; reducing capillary wall permeability and edema formation; decreasing complement components; antagonizing histamine activity and release of kinin from substrates; reducing fibroblast proliferation, collagen deposition, and subsequent scar tissue formation.

Precaution

Systemic absorption of topical corticosteroids may cause reversible hypothalamic-pituitaryadrenal (HPA) axis suppression, manifestations of cushing\'s syndrome, hyperglycemia, and glucosuria. Patients receiving large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid. Lactation: excretion of topical corticosteroids in breast milk is unknown; use with caution

Side Effect

Skin atrophy,Striae,Acneform lesions,Intracranial hypertension,Allergic contact dermatitis,Pruritus,Pustulation,Perioral dermatitis,Urticaria,Hypertrichosis,Leukoderma,Pigmentation changes,HPA suppression (with higher potency used >2 wk)