Largix

Largix5mg/5ml

Type:60ml

Generic Name:Rupatadine

Manufacturer:ACI Limited

Price:75.00

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Indication

Allergic rhinitis, Chronic idiopathic urticaria

Adult Dose

Oral Allergic rhinitis; Chronic idiopathic urticaria Adult: 10 mg (1 tablet) once daily.

Child Dose

Oral Allergic rhinitis; Chronic idiopathic urticaria Tablet Child > 12 years: 10 mg (1 tablet) once daily. Children: Use of Rupatadine is not recommended in patients less than 12 years of age. Syrup: Children aged 2 to 11 years: Children weighing 10 kg to less than 25 kg: 1/2 teaspoonful (2.5 ml) syrup once a day with or without food. Children weighing 25 kg or more: 1 teaspoonful (5ml) of syrup once a day with or without food.

Contraindication

Hypersensitivity. Avoid alcohol.

Mode of Action

Rupatadine acts as a long-acting, non-sedative antagonist at histaminergic H1-receptors. Rupatadine also antagonises the platelet-activating factor (PAF). Both histamine and PAF cause bronchoconstriction and lead to an increase in the vascular permeability, acting as mediators in the inflammatory process.

Precaution

Renal or hepatic insufficiency. May impair ability to drive or operate machinery. Pregnancy, lactation. Elderly, children <12 yr.

Side Effect

Headache, somnolence, fatigue/asthenia.

Interaction

Increased CNS depressant effects when used with CNS depressants or alcohol.

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