Enterobiasis, Ascariasis, Worm infections, Trichinosis
May be taken with or without food.
Oral Single or mixed infections due to susceptible worms Adult: 10 mg/kg as a single dose. Ascariasis Adult: 5 mg/kg as a single dose. Max: 1 g/dose. For mass treatment programmes: 2.5 mg/kg as a single dose given 3-4 times a yr. Necatoriasis Adult: 10 mg/kg daily for 3-4 days or 20 mg/kg daily for 2 days. Enterobiasis Adult: 10 mg/kg repeated once after 2-4 wk. Max dose: 1 g/dose. Trichinosis Adult: 10 mg/kg daily for 5 days.
<2 years: Safety and efficacy not established Oral Single or mixed infections due to susceptible worms Child: 10 mg/kg as a single dose.
Hypersensitivity
Pyrantel is effective against roundworms (Ascaris), threadworms (Enterobius), hookworms and Trichostrongylus. Not effective against whipworm. Acts by paralysing the worms which get detached and are excreted by intestinal peristalsis.
Liver dysfunction, anaemia or severe malnutrition. Treat members in close contact with the patient.
Anorexia, nausea, vomiting, abdominal cramps, drowsiness, insomnia, diarrhoea, tenesmus, SGOT elevations, headache, dizziness, rash.
Potentially Fatal: Mutually antagonistic with piperazine.