Cutisone

Cutisone0.005%

Type:10gm tube

Generic Name:Fluticasone Propionate 0.005% Topical

Manufacturer:General Pharmaceuticals Ltd.

Price:50.34

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Indication

Psoriasis, Eczema, Corticosteroid-responsive dermatoses

Adult Dose

Topical ointment Atopic Dermatitis, Corticosteroid-responsive Dermatoses Apply a thin film to the affected skin areas once or twice daily. Rub in gently. Reassess diagnosis if no improvements within 2 weeks

Child Dose

Topical ointment Atopic Dermatitis, Corticosteroid-responsive Dermatoses Child > 1 year: Apply a thin film to the affected skin areas once or twice daily.

Contraindication

Fluticasone Propionate ointment is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation.

Mode of Action

Fluticasone Propionate is a synthetic, trifluorinated corticosteroid that provides anti-inflammatory activity. It binds to glucocorticoid receptor and inhibits the migration of inflammatory mediator & cells (histamine, leukotrienes, mast cells, eosinophils etc).

Precaution

Fluticasone Propionate ointment may cause local cutaneous adverse reactions. If irritation develops, Fluticasone Propionate ointment should be discontinued. Fluticasone Propionate ointment should not be used in the presence of preexisting skin atrophy and should not be used where infection is present at the treatment site. This should not be used in the treatment of rosacea and perioral dermatitis. Lactation: Excretion in milk unknown; use with caution

Side Effect

1-10% Pruritus (2.9%),Dryness (1.2%),Skin irritation: (3%),Eczema (1%),Telangiectasia (2-5%),Numbness of fingers (1%) <1% Burning,Folliculitis,Acneiform lesions,Urticaria,Hypertrichosis,Lightheadedness,Viral,Warts,Impetigo,Skin infection Frequency Not Defined Striae,Pigmentation changes,HPA suppression (with higher potency used >2 wk),Erythema,Cushing syndrome,Sepsis,Hemorrhage reported,Edema/swelling

Pregnancy Category Note

Pregnancy Category: C Lactation: Excretion in milk unknown; use with caution

Interaction

May lead to increased plasma concentrations of fluticasone when used with CYP4503A4 inhibitors such as ritonavir.

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