Alfumax 2.5

Alfumax 2.52.5mg

Type:Tablet

Generic Name:Alfuzosin

Manufacturer:Unimed Unihealth Pharmaceuticals Ltd.

Price:0.00

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Indication

Oral Benign prostatic hyperplasia Adult: 2.5 mg tid. Max: 10 mg/day. 1st dose should be given before bedtime. Extended-release: 10 mg once daily. Elderly: Initially, 2.5 mg bid. Acute urinary retention: Extended-release: 10 mg once daily to be taken from 1st day of catheterisation. Duration: 3-4 days. Hepatic impairment: Mild to moderate: Initially, 2.5 mg daily, may increase to 2.5 mg bid according to response. Severe: Contraindicated.

Administration

Additive effect on QT interval prolongation when used w/ QT-prolonging drugs. Concomitant admin w/ other ?1-adrenergic blocking agents, atenolol or diltiazem may result in additive CV effects. Increased plasma alfuzosin concentrations w/ cimetidine. Potentially Fatal: Concurrent use w/ potent CYP3A4 inhibitors (e.g. ketoconazole, itraconazole, ritonavir) increase plasma alfuzosin levels.

Adult Dose

Elderly; hypertension; coronary insufficiency; angina (discontinue); renal or hepatic impairment. Monitor BP regularly. May affect ability to drive or operate machinery.

Renal Dose

Alfuzosin is a quinazoline derivative which exhibits selectivity for alpha1-adrenergic receptors in the lower urinary tract. Blockade of these adrenoreceptors causes relaxation of smooth muscle in the bladder neck and prostate, resulting in improvement in urine flow and a reduction in symptoms of benign prostatic hyperplasia (BPH).

Mode of Action

Administration Should be taken with food. Swallow whole. Extended-Release: Should be taken with food. Take immediately after the same meal each day. Swallow whole, do not chew/crush.

Precaution

Benign prostatic hyperplasia (BPH)

Side Effect

Renal Impairment Initially, 2.5 mg bid. Adjust dose according to response.

Pregnancy Category Note

1-10% Abdominal pain (1-2%),Back pain (1-2%),Brochitis (1-2%),Constipation (1-2%),Dizziness (5.7%),Dyspepsia (1-2%),Fatigue (2.7%),Headache (3%),Impotence (1-2%),Nausea (1-2%),Pharyngitis (1-2%),URT infection (3%),Sinusitis (1-2%),Upper respiratory infection (3%)

Interaction

Severe hepatic impairment; history of postural hypotension and micturition syncope; intestinal occlusion; severe renal insufficiency; lactation.

Alternative brand of Alfumax 2.5

ZatralZatral

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Price: ৳100.00

Eskayef Pharmaceuticals Ltd.

Alfumax ERAlfumax ER

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Price: ৳100.00

Unimed Unihealth Pharmaceuticals Ltd.

Alfasin XRAlfasin XR

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Price: ৳10.00

Incepta Pharmaceuticals Ltd.

UritenUriten

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Price: ৳10.07

Square Pharmaceuticals PLC.