Xolamid

Xolamid10mg/ml

Type:5ml bot

Generic Name:Brinzolamide 1% Eye prep

Manufacturer:Opsonin Pharma Limited

Price:501.50

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Indication

Open-angle glaucoma , ocular hypertension

Administration

May be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure; if more than one topical ophthalmic drug being used, administer at least ten min apart

Adult Dose

Adult: Ophth Open-angle glaucoma; Ocular HTN As 1% susp: Instill 1 drop 2-3 times/day.

Contraindication

Brinzolamide 1% ophthalmic suspension is contraindicated in patients who are hypersensitive to any component of this product.

Mode of Action

Brinzolamide is a carbonic anhydrase inhibitor that decreases secretion of aqueous humor thus reducing intraocular pressure.

Precaution

Hepatic and renal impairment; pregnancy. Efficacy has not been established in angle-closure glaucoma. Ensure an interval of at least 10 minutes between admin of different ophthalmic solutions. Lactation: Not known if distributed in breast milk; not recommedned (discontinue drug or do not nurse)

Side Effect

1-10% Blurred vision (5-10%),Dysgeusia (5-10%),Blepharitis (1-5%),Dermatitis (1-5%),Dry eye (1-5%),Foreign body sensation (1-5%),Headache (1-5%),Hyperemia (1-5%),Ocular discharge (1-5%),Ocular discomfort (1-5%),Ocular keratitis (1-5%),Ocular pain (1-5%),Ocular pruritus (1-5%),Rhinitis (1-5%) <1% Allergic reactions,Alopecia,Chest pain,Conjunctivitis,Diarrhea,Diplopia,Dizziness,Dry mouth,Dyspnea,Dyspepsia,Eye fatigue,Hypertonia,Keratoconjunctivitis,Keratopathy,Kidney pain,Lid margin crusting or sticky sensation,Nausea,Pharyngitis,Tearing,Urticaria

Pregnancy Category Note

Pregnancy Category: C Lactation: Not known if distributed in breast milk; not recommedned (discontinue drug or do not nurse)

Interaction

Brinzolamide: Concurrent use w/ oral carbonic anhydrase inhibitors may lead to additive systemic effects. Concurrent use w/ high-dose salicylates may lead to toxicity.

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