Type:Tablet
Generic Name:Ebastine
Manufacturer:The ACME Laboratories Ltd.
Price:৳6.00
Allergic rhinitis, Allergic conditions, Chronic idiopathic urticaria
May be taken with or without food.
Oral Allergic conditions Adult: 10-20 mg once daily.
Oral Allergic conditions Child: >6 yr: 5 mg once daily.
Hypersensitivity, cardiac arrhythmias.
Ebastine, a piperidine derivative, is a long-acting, nonsedating, second-generation histamine receptor antagonist that binds preferentially to peripheral H1 receptors. It is metabolised to active metabolite, carebastine. It has antihistaminic, antiallergic activity and prevents histamine-induced bronchoconstriction. It does not have significant sedative or antimuscarinic actions.
Caution is advised when used in hepatic impairment, renal insufficiency, QTc interval prolongation. Pregnancy, lactation.
Headache, dry mouth, drowsiness, pharyngitis, abdominal pain, dyspepsia, asthenia, epistaxis, rhinitis, sinusitis, nausea, insomnia.
Concomitant use of ketoconazole, itraconazole, clarithromycin or erythromycin may increase plasma levels of ebastine and cause QTc interval prolongation.
