Medicase - Pepcon Plus - Tablet - 480mg+20mg - Magaldrate + Simethicone Chewable

Pepcon Plus480mg+20mg

Type:Tablet

Generic Name:Magaldrate + Simethicone Chewable

Manufacturer:Leon Pharmaceuticals Ltd.

Price:৳3.10

Indication

Heartburn, Indigestion, Dyspepsia, Gastritis, Peptic ulcers, GERD

Administration

Take between meals & at bedtime.

Adult Dose

Oral Adult Tablet: 1-3 tablet, after meals and at bed time.

Child Dose

Oral Children 12 years and older: Tablet: 1-3 tablet, after meals and at bed time.

Contraindication

Patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal functions.

Mode of Action

Magaldrate is a hydroxymagnesium aluminate complex that is rapidly converted in gastric acid to magnesium and aluminium hydroxide, which is poorly absorbed and provides a sustained antacid effect with balanced efects on intestinal motility; increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying. Simethicone allows gas bubbles in the stomach and intestines to come together more easily, which allows for easier passage of gas.

Precaution

Care should be taken in decreased kidney function, hypophosphataemia and weak people.

Side Effect

Aluminum oxide Chalky taste,Constipation,Fecal impaction,Stomach cramps Frequency Not Defined Aluminum oxide Nausea,Vomiting,Aluminum intoxication,Hypophosphatemia,Osteomalacia, Magnesium oxide Diarrhea,Hypermagnesemia

Interaction

Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.