Type:Tablet
Generic Name:Carbimazole
Manufacturer:Renata Limited
Price:৳3.00
Grave's disease, Hyperthyroidism, Diabetic nephropathy, Preparation for thyroidectomy
May be taken with or without food. Take consistently w/ or w/o meals.
Oral Hyperthyroidism, Adjunct to radio-iodine therapy, Grave's disease, Preparation for thyroidectomy Adult: Initially, 20-60 mg daily as a single or divided dose, reduced gradually once euthyroidism is achieved. Maintenance: 5-15 mg daily for at least 1 yr or 18 mth. Hepatic impairment: Severe: Contraindicated.
Oral Hyperthyroidism; Adjunct to radio-iodine therapy; Preparation for thyroidectomy Child: 3-17 yr Initially, 15 mg daily, adjusted according to response.
Hyperthyroidism due to nodular goitre.
Carbimazole is metabolised to methimazole which is responsible for its antithyroid action. It blocks the production of thyroid hormones by inhibiting thyroid peroxidase.
Liver diseases, pregnancy, lactation.
Mild leucopaenia, sore throat, mouth ulcers, fever, bruising, malaise; rarely cholestatic jaundice; nephrotic syndrome. Nausea, loss of taste, headache, arthralgia, alopoecia. Potentially Fatal: Agranulocytosis, aplastic anaemia, hypoprothrombinaemia, neutropaenia; hypothyroidism and goitre.
Increased serum levels of theophylline or may develop toxicity. May enhance the effect of anticoagulants. Potentially Fatal: Increased sensitivity to warfarin in hyperthyroidism and careful control required as patient is rendered euthyroid.
