Gleek

Gleek80mg

Type:Tablet

Generic Name:Gliclazide

Manufacturer:United Chemicals & Pharmaceuticals Ltd.

Price:0.00

Ad

Indication

Type 2 DM

Administration

Should be taken 30 mintues before meal or with meal.

Adult Dose

Oral Type 2 diabetes mellitus Adult: Initially, 40-80 mg daily gradually increased to 320 mg daily if necessary. Doses >160 mg daily are given in 2 divided doses. Modified-release tab: Initially, 30 mg once daily, may increase in increments of 30 mg up to max 120 mg daily. Interval between doses should be at least 1 mth. For non-respondent patients, dose may be increased after 2 wk.

Contraindication

Type 1 DM, diabetes complicated with ketoacidosis; hypersensitivity; severe renal and hepatic impairment. Pregnancy and lactation.

Mode of Action

Gliclazide stimulates insulin secretion from pancreatic beta-cells, reduces insulin uptake and glucose output by the liver, and increases insulin sensitivity at peripheral target sites. It decreases microthrombosis by partial inhibition of platelet aggregation and adhesion, and by restoring fibrinolysis w/ an increase in tissue plasminogen activator (t-PA) activity.

Precaution

Monitor blood glucose concentration. May require insulin during metabolic stress. Care when transferring from combination therapy. Increased risk of severe hypoglycaemia in elderly, debilitated patients, patients with hepatic or renal impairment. Risk of hypogylcaemia when caloric intake is deficient, after strenuous exercise, when taken with ethanol or when >1 antidiabetic drug is used.

Side Effect

GI disturbances, skin reaction, leucopenia, thrombocytopenia, agranulocytosis, haemolytic anaemia, cholestatic jaundice, vomiting, diarrhoea, gastritis, increased transaminases.

Interaction

May increase hypoglycaemic effect w/ phenylbutazone. Potentiation of blood glucose lowering effect w/ other antidiabetics (e.g. acarbose, insulins, metformin), beta-blockers, ACE inhibitors, H2-receptor antagonists, MAOIs, sulfonamides, clarithromycin and NSAIDs. Chlorpromazine, glucocorticoids, ritodrine, salbutamol and terbutaline may cause increases in blood glucose levels. May diminish hypoglycaemic effect w/ danazol. May increase anticoagulant effect of warfarin. Potentially Fatal: Increased hypoglycaemic effect w/ miconazole

Alternative brand of Gleek

Glikazid MR 30Glikazid MR 30

  • 30mg
  • Tablet
  • Gliclazide

Price: ৳70.00

Eskayef Pharmaceuticals Ltd.

Glikazid MR 60Glikazid MR 60

  • 60mg
  • Tablet
  • Gliclazide

Price: ৳120.00

Eskayef Pharmaceuticals Ltd.

Glikazid 80Glikazid 80

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳80.00

Eskayef Pharmaceuticals Ltd.

Dimerol MR 60Dimerol MR 60

  • 60mg
  • Tablet
  • Gliclazide

Price: ৳110.00

Drug International Ltd.

Remicron MR 60Remicron MR 60

  • 60mg
  • Tablet
  • Gliclazide

Price: ৳120.00

Sun Pharmaceutical (Bangladesh) Ltd.

Consucon 60 MRConsucon 60 MR

  • 60mg
  • Tablet
  • Gliclazide

Price: ৳120.00

Incepta Pharmaceuticals Ltd.

Diapro 80Diapro 80

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳105.00

Beximco Pharmaceuticals Ltd.

Dimerol 80Dimerol 80

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳112.00

Drug International Ltd.

OrazidOrazid

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳7.00

Somatec Pharmaceuticals Ltd.

DigreenDigreen

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳0.00

Nipa Pharmaceuticals Ltd.

Gored MRGored MR

  • 30mg
  • Tablet
  • Gliclazide

Price: ৳124.04

General Pharmaceuticals Ltd.

Diamicron MR 30Diamicron MR 30

  • 30mg
  • Tablet
  • Gliclazide

Price: ৳360.00

Servier Bangladesh Operation

Gle 80Gle 80

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳0.00

Asiatic Laboratories Ltd.

GlucoactGlucoact

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳6.01

Veritas Pharmaceuticals Ltd.

GideGide

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳6.00

Medicon Pharmaceuticals Ltd.

Glix 80Glix 80

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳80.00

Navana Pharmaceuticals Ltd.

Radizid XR 30Radizid XR 30

  • 30mg
  • Tablet
  • Gliclazide

Price: ৳70.00

Radiant Pharmaceuticals Ltd.

Gored 80Gored 80

  • 80mg
  • Tablet
  • Gliclazide

Price: ৳70.10

General Pharmaceuticals Ltd.

Kezid MRKezid MR

  • 30mg
  • Tablet
  • Gliclazide

Price: ৳8.00

Kemiko Pharmaceuticals Ltd.

Remicron MR 30Remicron MR 30

  • 30mg
  • Tablet
  • Gliclazide

Price: ৳80.00

Sun Pharmaceutical (Bangladesh) Ltd.