Type:5ml drop
Generic Name:Gentamicin + Hydrocortisone Acetate Ear prep
Manufacturer:OSL Pharma Limited,
Price:৳55.20
Treatment of, chronic suppurative otitis media, otitis externa, and as prophylactic treatment of otitis externa following trauma, post-operative local use in surgery to infected mastoid cavities.
Middle Ear Infection: Instill 2-4 drops in the affected ear three to four times a day and at night, or more frequently if required. Ear Canal Infection: Instill 2-4 drops in the affected ear three to four times a day and at night, or more frequently if required.
Contraindicated in patients with known or suspected perforation, or where there is a risk of perforation of the tympanic membrane. Known hypersensitivity to Hydrocortisone or Gentamicin or any other components of the product.
Gentamicin is mixture of antibiotic substances produced by the growth of micromonospora purpurea. It is a bactericidal antibiotic which acts by inhibiting protein synthesis. It has greater antibacterial activity than streptomycin, neomycin or kanamycin. Gentamicin exerts a number of effects on cells of susceptible bacteria. It affects the integrity of the plasma membrane and the metabolism of RNA, but it's most important effect is inhibition of protein synthesis at the level of the 30s ribosomal subunit. Corticosteroids, such as hydrocortisone acetate, are used in pharmacological doses for their anti-inflammatory and immuno-suppressant glucocorticoid properties which suppress the clinical manifestation of disease in a wide range of disorders
Long-term continuous therapy should be avoided. Prolonged use may result in overgrowth of non-susceptible organisms, including fungi. If an infection is not improved after one week, cultures and susceptibility tests should be performed to verify the identity of the organism and to determine what alternative therapy should be installed.
Ear discomfort, ear irritation may occur in rare cases. Gentamicin may cause irreversible partial or total deafness when given systemically or when applied topically to open wounds or damaged skin.
Pregnancy Safety for use in pregnancy has not been established. Topical administration of any corticosteroid to pregnant animals can cause abnormalities of foetal development. This medicine should only be used in pregnancy when considered essential by the physician, after careful assessment of the potential risks and benefits. Lactation Safety for use in lactation has not been established. This medicine should only be used in lactation when considered essential by the physician, after careful assessment of the potential risks and benefits.
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