Type:Tablet
Generic Name:Etodolac
Manufacturer:The ACME Laboratories Ltd.
Price:৳15.04
Rheumatoid arthritis, Pain, Osetoarthritis
Should be taken with food. Take w/ or immediately after meals.
Oral Osteoarthritis; Rheumatoid arthritis Adult: 600-1000 mg/day in divided doses adjusted according to response. Max: 1200 mg/day. ER tablet: Once daily Hepatic impairment: Dose adjustment not necessary
Juvenile Rheumatoid Arthritis <6 years Safety and efficacy not established 6-16 years 20-30 kg (extended release): 400 mg PO once daily 31-45 kg (extended release): 600 mg PO once daily 46-60 kg (extended release): 800 mg PO once daily >60 kg (extended release): 1000 mg PO once daily
Mild-to-moderate renal impairment: Dose adjustment not necessary Severe renal impairment; Not recommended
Peptic ulcer, hypersensitivity to etodolac/NSAIDs. Childn; pregnancy (3rd trimester) and lactation.
Etodolac is an NSAID derived from pyrano-indoleacetic acid, inhibits cyclooxygenase 2 (COX-2) resulting in decreased prostaglandin precursor formation.
CHF, dehydration, impaired renal, hepatic function, history of GI disease. Elderly, patients receiving anticoagulant. Lactation: Unknown whether drug is excreted in breast milk; not recommended
1-10% Dyspepsia (10%),Dizziness (3-9%),Nervousness (1-3%),Pruritus (1-3%),Blurred vision (1-3%),Depression (1-3%),Chills/fever (1-3%) >1% Asthenia, malaise,Blurred vision,Bronchospasm,Dysuria, urinary frequency,Edema,Melena,Rash,Tinnitus Potentially Fatal: Acute renal failure; blood disorder; nephrotoxicity; angioedema, arrhythmia, bone marrow suppression, CHF, dyspnoea, erythema multiforme, exfoliative dermatitis, hepatitis, hypertension, peripheral neuropathy, Stevens-Johnson syndrome, syncope, tachycardia, toxic amblyopia, toxic epidermal necrolysis, urticaria.
Pregnancy category: C; avoid in late pregnancy (may cause premature closure of ductus arteriosus) Lactation: Unknown whether drug is excreted in breast milk; not recommended
Increased effect of warfarin, lithium, methotrexate, digoxin, cyclosporin, aspirin. Effect may be reduced with aspirin. Reduced effect of some diuretics and ?-blockers. Alcohol enhances gastric mucosal irritation.
