D-Pira

D-Pira800mg

Type:10 Tablets

Generic Name:Piracetam

Manufacturer:Drug International Ltd.

Price:60.00

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Indication

Cortical myoclonus, Cognitive enhancer

Administration

Oral soln: May be taken with or without food. Take w/ a glass of water or soft drink to mask bitter taste.

Adult Dose

Oral Adjunct in cortical myoclonus Adult: 7.2 g daily in 2-3 divided doses, increased by 4.8 g/day every 3-4 days. Max dose: 20 g daily. As a cognitive enhancer in cerebrocortical insufficiency Adult: 2.4 g daily, given as 2-3 divided doses. Up to 4.8 g daily may be used in severe cases.

Child Dose

<16 years old: not recommended > 16 yeras The daily dosage depends on the weight, 50 mg/kg of body weight in 3 divided doses. Once the desired results has been obtained, reduce the initial dose by half.

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation 50-79 2/3 usual dose 30-49 1/3 usual dose 20-29 1/6 usual dose <20 Contra-indicated

Contraindication

Hepatic and severe renal impairment. Cerebral haemorrhage. Pregnancy and lactation.

Mode of Action

Piracetam protects the cerebral cortex against hypoxia. It also inhibits platelet aggregation and reduces blood viscosity.

Precaution

Avoid abrupt withdrawal. Impaired renal function. Cardiac disorders. Haemostatic disorders. Patients who have recently undergone major surgery. Elderly. Lactation: contraindicated

Side Effect

Hyperkinesia, nervousness, depression, diarrhoea, rashes. CNS stimulation, sleep disturbances, dizziness, excitement, insomnia, somnolence, wt gain.

Interaction

May increase prothrombin time in patients who are on warfarin.

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