Type:Injection
Generic Name:Vinpocetine
Manufacturer:General Pharmaceuticals Ltd.
Price:৳40.12
Dementia, Cerebrovascular disorders, Stroke
Should be taken with food. Take after meals.
Oral Adult Tablet: 1-2 tablets thrice daily, the maintenance dose is 1 tablet thrice daily. Parenteral IM Injection: Daily dose of 20-40 mg are to be given until improvement of symptoms is reached (for not longer than 10 days) then oral treatment should be applied. If this regimen fails, infusion treatment should be started. IV Infusion: The daily starting dose is 20 mg in slow drip infusion (2 ampoules in 500-1000 ml infusion solution). This dose can be increased to 1 mg/kg body weight during 3 to 4 days. Treatment should be continued for 10-14 days depending on the tolerance of the patients and the dose should be gradually reduced before discontinuation of treatment.
Parenteral treatment- Severe ischaemic heart disease, severe rhythm disorders and pregnancy. Pregnancy, Lactation.
Vinpocetine is derived from vincamine. It increases cerebral circulation and utilisation of oxygen and is used in a variety of cerebral disorders. Shown to inhibit cGMP phosphodiesterase that has may result in increased cerebral blood flow. Reported to have calcium-channel blocker, voltage-gated sodium channel blocker, & acetylcholine release activities.
Hypertension or cardiac dysfunction. In the acute stage until the improvement of symptoms parenteral treatment is recommended followed by oral treatment. In chronic cases oral therapy should be applied.
Transient hypotension, tachycardia.
Possible decrease in anticoagulation effect with warfarin.
