Type:Tablet
Generic Name:Celiprolol Hydrochloride
Manufacturer:Eskayef Pharmaceuticals Ltd.
Price:৳15.00
Hypertension, Angina pectoris
Should be taken on an empty stomach. Take at least ½ hr before or 2 hr after meals.
Oral Hypertension Adult: 200-400 mg once daily.
Renal impairment: CrCl (ml/min) 15-40 100-200 mg/day. <15 Avoid.
Hypersensitivity, sinus bradycardia, >1st degree heart block, cardiogenic shock, uncompensated heart failure, hypotensive patients. Pregnancy (2nd and 3rd trimesters).
Celiprolol is a cardioselective ?-blocker. It exhibits intrinsic sympathomimetic and direct vasodilator activity.
Asthma. Lactation.
Nausea, abdominal discomfort, diarrhoea; CHF, AV nodal block and bradycardia, palpitations; headache, fatigue, dizziness, insomnia; Raynaud's phenomenon; orthostatic hypotension; bronchial obstruction; tremor, rash, muscle cramps; impotence.
Pregnancy Category B in (1st trimester), D in 2nd & 3rd trimesters.
May exacerbate rebound HTN upon withdrawal of clonidine. May increase AV conduction time w/ digitalis glycosides. Reduced bioavailability w/ concomitant hydrochlorothiazide, chlorthalidone or theophylline. Concomitant dihydropyridine Ca channel blockers (e.g. nifedipine) may increase the risk of hypotension and heart failure.